Treos Bio Limited (“Treos”), a clinical stage biotechnology company using data science and proprietary biomarkers to develop precision peptide immunotherapies, today announced that the first patient has been dosed in the OBERTO 201 Phase 1b trial of PolyPEPI1018, the Company’s lead product candidate, as an add-on to standard-of-care third-line chemotherapy (TAS-102) for the treatment of patients with late-stage microsatellite stable (MSS) metastatic colorectal cancer (mCRC).

Treos Bio Limited (“Treos”), a clinical stage biotechnology company using data science and proprietary biomarkers to develop both precision off-the-shelf and personalized peptide immunotherapies for cancer, today announced that the U.S. Food and Drug Administration (FDA) has cleared the Investigational New Drug (IND) application for PolyPEPI1018, the Company’s lead product candidate, as an add-on to third-line chemotherapy (TAS-102) for the treatment of patients with late-stage metastatic colorectal cancer (mCRC).

Treos Bio Limited (“Treos”), a clinical stage biotechnology company using data science and proprietary biomarkers to develop both precision off-the-shelf and personalized peptide cancer immunotherapies, today announced a clinical collaboration with Roche in which Treos will evaluate the combination of PolyPEPI1018, its lead product candidate, and atezolizumab, Roche’s PD-L1-inhibitor, in patients with late stage microsatellite stable metastatic colorectal cancer (MSS mCRC). A Phase I/II trial evaluating PolyPEPI1018 in combination with atezolizumab is expected to begin in Q4 2021.

Treos Bio Limited (“Treos”), a clinical stage biotechnology company using data science and proprietary biomarkers to develop precision off-the-shelf and personalized peptide cancer immunotherapies, today announced the publication of a peer-reviewed article titled “A Peptide Vaccine Candidate Tailored to Individuals’ Genetics Mimics the Multi-Targeted T Cell Immunity of COVID-19 Convalescent Subjects” in Frontiers in Genetics. The paper reviewed the potential of PolyPEPI-SCoV-2, the Company’s peptide vaccine candidate, to potentially address all four structural proteins of the COVID-19 virus in order to generate long-term immunity in virtually all human subjects, independent of ethnicity.

Treos Bio Limited (“Treos”), a clinical stage biotechnology company using data science and proprietary biomarkers to develop precision off-the-shelf and personalized peptide cancer immunotherapies, today announced the appointment of Ruti Alon to its Board of Directors. Ms. Alon joins Treos with over 40 years of executive and entrepreneurial expertise as a life sciences investor, mentor and leader for private and public biotechnology companies.

Treos Bio Limited (“Treos”), a clinical stage biotechnology company using data science and proprietary biomarkers to develop precision off-the-shelf and personalized peptide cancer immunotherapies, today announced that it closed a $14 million convertible loan note financing. The financing was led by Luminous Ventures and the UK Government’s Future Fund, both first-time investors in Treos. In addition, Isabel Fox, Co-Managing Partner of Luminous Ventures, joined Treos’ Board of Directors.

Treos Bio Limited, a clinical stage biopharma company developing precision peptide cancer immunotherapies, today presented positive final data from a Phase I/II study of PolyPEPI1018, its off-the-shelf multi-peptide treatment, in microsatellite stable metastatic colorectal cancer (MSS mCRC) patients during an online poster presentation released today at the 2020 ASCO Annual Meeting.

Treos Bio has developed a unique approach to create cancer vaccines by focusing not just on the vaccine targets but also on delivering antigen targets to which each patient’s immune system can specifically respond. Its proprietary class-leading platform, the Personal Antigen Selection Calculator (PASCal), addresses both patient and tumor heterogeneity. PAScal enabled the development of two families of effective shared antigen-based cancer vaccines (“off-the-shelf” and “personalized”) that target 19 cancer indications and are commercially scalable, without need for tumor biopsy and on-demand manufacturing.

Treos Bio Limited, which is developing personal cancer vaccines combined with companion diagnostic devices, reported updated positive results on the second part of its phase 1/2 study (OBERTO) with the PolyPEPI1018 cancer vaccine as an add-on to maintenance therapy in patients with microsatellite-stable (MSS) metastatic colorectal cancer (mCRC).

Treos Bio Limited, an immuno-oncology company developing next-generation, precision cancer vaccines combined with companion diagnostic devices, reported positive interim results from its first-in-man Phase 1/2 study of its precision cancer vaccine with maintenance therapy in patients with metastatic colorectal cancer (mCRC).